In the late 19th and early 20th centuries Bow was spiritually divided between the Church of England, the Congregationalists and the Plymouth Brethren.
This was a strongly proselytizing church influenced by Plymouth Brethren ideas of church polity, rather exclusivist and often in conflict with denominational and mission churches.
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From the mid-1920s onward Watchman Nee, strongly influenced by Plymouth Brethren ideas (especially premillennialism) but also by a stress on the Holy Spirit derived from the Holiness tradition, was an inspiring and compelling teacher.
The Salvation Army have an active corps here and the 'Closed' Plymouth Brethren have two meeting rooms as their church halls are generally known.
In 1884 the Plymouth Brethren missionary Frederick Stanley Arnot traveled through the region and identified the source of the Zambezi.
His overall theology could be generally described as based on the inductive study of the entire Bible, having similarities to John Darby of the Plymouth Brethren, Calvinism, a mild form of Keswick Theology on Sanctification, and Presbyterianism, all of these tempered with a focus on spirituality based on simple Bible study and living.
Samuel Trevor Francis (1834–1925) was an English lay preacher and hymn writer, with the Plymouth Brethren.
Robert trains to be a doctor at the fictional Levenford Infirmary (Levenford is loosely based on Dumbarton), and falls in love with Jean Law, a young medical student belonging to the Plymouth Brethren who rejects him when she discovers that he has deceived her about his history and religion (he is a Roman Catholic).
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Upward was brought up as a member of the Plymouth Brethren and trained as a lawyer at the Royal University of Dublin (now University College Dublin).
It was the BSAC's failure to get Msiri to sign up Garanganza as a British Protectorate which lost the Congolese Copperbelt to Northern Rhodesia, and some in the BSAC complained that the British missionaries Frederick Arnot and Charles Swan could have done more to help, although their Plymouth Brethren mission had a policy of not being involved in politics.
When she was a teenager, her parents separated and she went to live in Exeter with her grand-aunt, then in Devon where she joined the evangelical Christian Plymouth Brethren.
The feud ultimately led to the division of the Plymouth Brethren in 1848 when George Muller, the co-leader of Bethesda chapel, a brethren assembly in Bristol, allowed visitors from Ebrington Street into fellowship in Bristol and was slow to comply to Darby's ultimatum for all assemblies to condemn Newton's heresy.
Christopher James Davis (1842–1870), doctor and member of the Plymouth Brethren
He was associated numerous principal men of the Plymouth Brethren movement including William Kelly, J.G. Bellett, John Nelson Darby, George Wigram.