The station was opened on 1 September 1880, upon the inauguration of the Picerno–Potenza section of the Battipaglia–Potenza–Metaponto railway, a line linking it directly with Salerno and Taranto.
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The more common regional trains link Potenza with closer destinations, including Salerno, Naples, Melfi, Foggia and Taranto.
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In the other direction, towards Battipaglia, there are several small buildings used for various technical purposes, and above them the concrete Musmeci viaduct, which provides road access to the city.
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