His family moved to his sister-in-law's in Sussex to escape the fever, which eventually killed six children in the village of Downe.
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Joseph Dalton Hooker, John Tyndall and Thomas Huxley now formed a group of young naturalists holding Darwin in high regard, basing themselves in the Linnean Society of London which had just moved to Burlington House, Piccadilly, London, near the Royal Society.
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Charles gained much useful information from his relatives during the inception of Darwin's theory, and it was at Maer Hall that he first became interested in the effects of earthworms which were the subject of an early paper presented to the Geological Society as well as of his last book.