X-Nico

6 unusual facts about Rett syndrome


Anna Stanley

Instead Stanley devoted time to motherhood, and in 2007 became an Ambassador for Rett New Zealand, an organisation to assist children and their families that suffer from Rett syndrome.

F-15,599

Neurolixis announced that it intends to re-purpose F-15,599 for the treatment of Rett syndrome.

Rett

Rett syndrome, neurodevelopmental disorder of the grey matter of the brain that affects girls almost exclusively

Rett syndrome

In less than 10% of RTT cases, mutations in the genes CDKL5 or FOXG1 have also been found to resemble it.

Zappella variant of Rett Syndrome or preserved speech variant: in this subtype of Rett syndrome the patients acquire some manual skills and language is partially recovered around the age of 5 years (that is after the regression phase).

An atypical form of RTT, characterized by infantile spasms or early onset epilepsy, can also be caused by a mutation to the gene encoding cyclin-dependent kinase-like 5 (CDKL5).


Huda Zoghbi

Her residency as a neurological pediatrician brought Rett syndrome to her attention, and she learned molecular genetics from Arthur Beaudet in order to do research on Rett's and other genetic neurological disorders.


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