Aldolase has also been implicated in many "moonlighting" or non-catalytic functions, based upon its binding affinity for multiple other proteins including F-actin, α-tubulin, light chain dynein, WASP, Band 3 anion exchanger, phospholipase D (PLD2), glucose transporter GLUT4, inositol trisphosphate, V-ATPase and ARNO (a guanine nucleotide exchange factor of ARF6).
It also inhibits cdc42 by binding to its tail and preventing its insertion into membranes; hence it cannot trigger WASPs and cannot lead to nucleation of F-actin.
protein | Down syndrome | Protein subunit | Protein-protein interaction | Tourette syndrome | Asperger syndrome | Hfq protein | protein domain | Protein-protein_interaction | Robert Aldrich | Marfan syndrome | Protein Data Bank | Kate Aldrich | Down Syndrome | Turner syndrome | RNA-binding protein | Down's syndrome | Asperger's syndrome | Williams syndrome | Stockholm syndrome | Severe acute respiratory syndrome | Ronnie Aldrich | Rett syndrome | Promyelocytic leukemia protein | Irukandji syndrome | G protein | Chronic fatigue syndrome | Aldrich Contemporary Art Museum | Wiskott–Aldrich syndrome protein | Tourette Syndrome Association |
According to the New England Ski Museum, the first recorded use of skis on Mount Washington was by a Dr. Wiskott of Breslau, Germany, who skied on the mountain in 1899, while the first skier in Tuckerman was John S. Apperson of Schenectady, New York, in April 1914.