Ribose-5-phosphate isomerase deficiency is mutated in a rare disorder, Ribose-5-phosphate isomerase deficiency.
phosphate | Nicotinamide adenine dinucleotide phosphate | Phosphate | British Phosphate Commission | Ribose | Imidazoleglycerol-phosphate dehydratase | Glucose-6-phosphate dehydrogenase deficiency | Triosephosphate isomerase | Ribose-5-phosphate isomerase deficiency | ribose | Phosphate minerals | Phosphate conversion coating | Pentose phosphate pathway | Nauru Phosphate Corporation | N-acetylglucosamine-1-phosphate transferase | lithium iron phosphate | Glucose-6-phosphate dehydrogenase | Dihydroxyacetone phosphate | Dicalcium phosphate |
They contain – in contrast to most nucleosides – instead of the Dβ-D-Arabinofuranose.
cADPR and ADPR are synthesized from NAD+ by the bifunctional ectoenzymes of the CD38 family (also includes the GPI-anchored CD157 and the specific, monofunctional ADP ribosyl cyclase of the mollusc Aplysia).
It is a derivative of the nucleoside adenosine, differing from the latter by the replacement of a hydroxyl group (-OH) by hydrogen (-H) at the 2' position of its ribose sugar moiety.
The hsrω-n transcript directly or indirectly affects the localization/stability/activity of a variety of proteins including hnRNPs, Sxl, Hsp83, cAMP response element binding binding protein (CBP), Drosophila inhibitor of apoptosis protein 1 (DIAP1), JNK-signalling members, proteasome constituents, lamin C, ISWI, HP1 and poly(ADP)-ribose polymerase.
Uridine phosphorylase adds ribose-1-phosphate to the free base uracil, forming uridine monophosphate.
cAMP and cGMP, formed from ATP and GTP, serve as secondary messengers in some signalling pathways.