As an avid naturalist, Brent is a member of the Society of Animal Artists and has created sculptures of numerous of birds and mammals; some of these are large bronze sculptures which he has donated for his young patients and other children to enjoy in the San Diego Zoo and San Francisco Zoo.
He was a structural engineer and helped lay out the aquatic features of the San Diego Zoo.
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The museum has the largest collection of different species of live rattlesnakes in the world, which are presented in recreated habitats, and claims to host more species than the Bronx Zoo, the Philadelphia Zoo, the National Zoo in Washington, D.C., the Denver Zoo, the San Francisco Zoo, and the San Diego Zoo combined.
She assisted with critical research on Giant Pandas including work on panda breeding at the Center for Reproduction of Endangered Species (now called the Institute for Conservation Research), a research arm of the San Diego Zoo and San Diego Zoo Safari Park.
The Anegada ground iguana has also been successfully bred in captivity at the San Diego Zoo and the Fort Worth Zoo.
Ken Allen (1971–2000), name given to a Bornean orangutan at the San Diego Zoo