The song was showcased as part of Dolby's appearance at the South by Southwest 2007 music festival.
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Although a success in the United States, peaking at No. 5 in the Billboard Hot 100 and 2 weeks at No. 1 in Canada's RPM Magazine, the song barely managed to score among the Top 50 in Dolby's native United Kingdom, peaking at No. 49 in the UK Singles Chart.
Bachelor of Science | National Science Foundation | American Association for the Advancement of Science | political science | Master of Science | Science | Computer Science | computer science | science | Political Science | Mystery Science Theater 3000 | Norwegian University of Science and Technology | science fiction film | Weizmann Institute of Science | Science fiction | Indian Institute of Science | The Christian Science Monitor | Science (journal) | Intel International Science and Engineering Fair | Science Applications International Corporation | National Medal of Science | Computer science | The Magazine of Fantasy & Science Fiction | American Political Science Association | Science Museum | Political science | Hong Kong University of Science and Technology | Science Museum (London) | Social Science Research Council | Science Olympiad |
Her cover of "He Blinded Me With Science" appeared on the soundtrack to Jimmy Neutron: Boy Genius.