Flexner–Wintersteiner rosettes were first described by Simon Flexner (1863–1946), a physician, scientist, administrator, and professor of experimental pathology at the University of Pennsylvania (1899–1903).
The species was named after the American physician Simon Flexner, in addition to the Japanese physician Kiyoshi Shiga, who researched the cause of dysentery.
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Eleanor’s father, Abraham Flexner (1866-1959), was a leader in several fields including, with his brother Simon Flexner at the Rockefeller Institute, the reform of early 20th-century medical education and medical research in the United States and Canada.