Sir | Sir Walter Scott | 3rd Rock from the Sun | baronet | Baronet | Sir Arthur Conan Doyle | South Carolina's 3rd congressional district | Robert Gascoyne-Cecil, 3rd Marquess of Salisbury | Sir Robert Peel | Michigan's 3rd congressional district | Thomas Fairfax, 3rd Lord Fairfax of Cameron | 3rd United States Congress | Fernando Álvarez de Toledo, 3rd Duke of Alba | 3rd arrondissement of Marseille | Sir Arthur Harris, 1st Baronet | Sir Raylton Dixon | Sir Harold Hillier Gardens | Sir Fitzroy Maclean, 1st Baronet | Sir Francis Baring, 1st Baronet | Sir William Temple, 1st Baronet | Henry John Temple, 3rd Viscount Palmerston | Thomas Radclyffe, 3rd Earl of Sussex | Sir Richard Fanshawe, 1st Baronet | Richard of York, 3rd Duke of York | John Stuart, 3rd Earl of Bute | Alabama's 3rd congressional district | 3rd Battalion | William Cavendish-Bentinck, 3rd Duke of Portland | Sir William Johnson, 1st Baronet | Sir Robert Eden, 1st Baronet, of Maryland |
His father, William Harcourt Isham Mackworth (1806—1872), a younger son of Sir Digby Mackworth, the 3rd Baronet, took the additional surname Dolben after he married Frances, the heiress of Sir John English Dolben, the 4th Baronet.
He established an influential international network that included Giuseppe Garibaldi, Christian Charles Josias Bunsen and Frederick William IV of Prussia.
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Born London, his father, Sir Culling Smith, 2nd Baronet (1768–1829), was of Huguenot extraction and his mother, Charlotte Elizabeth (d. 15 Sept 1826) was the daughter of Sampson Eardley, 1st Baron Eardley, and hence the granddaughter of Jewish financier Sampson Gideon.