Spasms can be caused by a disparity between how much alpha and gamma motor neurons are firing i.e. too much gain of one or the other.
Spasms |
In most cases of infantile spasms, hypsarrhythmia either disappears or improves during a cluster of spasms and/or REM sleep.
An atypical form of RTT, characterized by infantile spasms or early onset epilepsy, can also be caused by a mutation to the gene encoding cyclin-dependent kinase-like 5 (CDKL5).
His later screenwriting credits include Rip-Off, Wedding in White, Slipstream, Death Weekend, Spasms and Imaginary Playmate, while his film directing credits include Wedding in White, Death Weekend, Spasms, Search and Destroy, Killer Party, Cries in the Night and Bedroom Eyes.