For instance, mouse tissue is approximately fifty times less responsive than human tissue to the venom of the Sydney funnel-web spider.
However, it remains, together with the northern tree funnel-web, the only Australian funnel-web spider known to have inflicted fatal bites to humans.
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Omega-atracotoxin is an insect-specific neurotoxin of Blue mountains funnel-web spiders whose phylogenetic specificity derives from its ability to antagonise insect, but not vertebrate, voltage-gated calcium channels.
In a DVD commentary, Jackson says Shelob's appearance is mostly based on the New Zealand tunnel-web spider, which he hates.