The book chronicles the Acid Tests (parties in which LSD-laced Kool-Aid was used to obtain a communal trip), the group's encounters with (in)famous figures of the time, including famous authors, Hells Angels, and The Grateful Dead, and it also describes Kesey's exile to Mexico and his arrests.
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He took the parties to public places, and advertised with posters that read, "CAN YOU PASS THE ACID TEST?", and the name was later popularized in Tom Wolfe's 1968 book, The Electric Kool-Aid Acid Test.
Part Six, "Interpenetration of Meanings", provides an excerpt from D. R. Venables and R. E. Clifford, Academic Dress of the University of Oxford (1957), as well as from Tom Wolfe's The Electric Kool-Aid Acid Test (1968), from an anonymous 19th-century etiquette manual (1872), from Lucy Grace Allen's Table Service (1915), and from the 7th edition of Ceremonies of the Roman Rite Described (1943) by Adrian Fortescue and John Berthram O'Connell.