He associated with a number of celebrities of his times, including Jean-Martin Charcot, Louis Pasteur, Henry James, and Guy de Maupassant, all of whom figure in the book.
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His decades-long service as personal physician and confidante to the Queen of Sweden is mentioned only in the most oblique terms; at one point, while naming her only as "she who must be mother to a whole nation", he mentions that she regularly brings flowers for the grave of one of her dogs buried at Villa San Michele, at another point, one of his servants is out walking his dogs, and encounters the Queen, who mentions having given the dog to Munthe.
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The few remains of the Tiberian villa Damecuta are the result of excavations done between 1937-48 by Maiuri (who also excavated Villa Jovis), on land donated to the Italian Government by Axel Munthe, celebrated author of The Story of San Michele.