Theodore I Laskaris came to accept it in a 1206 agreement with Kaykhusraw I.
At about the same time his brother Constantine Laskaris was unsuccessfully proclaimed emperor by some of the defenders of Constantinople.
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In spite of this defeat, Theodore was able to take advantage of the death of David Megaskomnenos, the brother of Emperor Alexios I of Trebizond in 1212 and to extend his own control over Paphlagonia.
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His son-in-law, Theodore Laskaris, who was the only one to attempt anything significant, was defeated at Scutari, and the siege of Constantinople began.
He had been betrothed to Eudoxia on a former occasion; the circumstances surrounding the failed negotiations are unclear, but George Akropolites states that the arrangement was blocked on religious grounds by the Orthodox Patriarch Manuel Sarantenos: Robert's sister Marie de Courtenay was married to Emperor Theodore I Laskaris.