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After the start of the Egyptian Revolution of 2011, Galal Amer was one of the people that opposed Hosni Mubarak and Supreme Council of the Armed Forces, and participated in the demonstration protests that demanded the end of military rule.
The foreign, justice, interior, and oil ministers resigned and three new ministers were named: General and former governor of Minya, Mansour El Essawi, became interior minister; Mohamed Abdel Aziz Al-Guindy became justice minister; and former judge Nabil Elaraby was appointed foreign minister.