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According to the Toba catastrophe theory 75,000 to 80,000 years ago a super volcanic event at Lake Toba reduced the human population to 10,000 or even 1,000 breeding pairs creating a bottleneck in human evolution.
Also this subduction zone has created arguably the world's largest active volcano Lake Toba which produced the largest volcanic eruption in human history erupting just over 2,800 km³ of magma, a VEI of 8.