One exception is David Brin's Uplift Universe; here, hyperspace is divided into "levels" where time passes at different rates.
David Brin's science fiction series about the Uplift Universe is also often mentioned as inspiration for the Star Control II universe, as well as Larry Niven's Known Space universe.
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Animals, too, can be given the intelligence of a human being through bioscientific techniques, a concept explored previously by David Brin in his Uplift novels,Roger Zelazny in The Dream Master, and in Olaf Stapledon's Sirius.