Later on, the control of commerce with the territories of Guinea and Elmina, rich in gold and slaves, grew to a dispute of even greater importance.
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In February 1479, Isabelle and Ferdinand tried to organize a new fleet of about twenty caravels to expel the Portuguese from Elmina.
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He had been regaining power while his rival, the Duke of Medina Sidonia, initially the main Isabella supporter in Andalusia, had been falling into dishonour.
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The bulk of the Portuguese army was able to take refuge in Mérida and from there continued its march to Medellín, which they occupied.
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At the beginning of 1478, the monarchs prepared two new expeditions from the port of Sanlúcar de Barrameda, one directed towards Elmina and the other, consisting of at least 35 ships, with the aim of conquering the island of Gran Canaria.
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His objective was to occupy and reinforce the strongholds of Mérida and Medellín, controlled by Beatriz Pacheco, Countess of Medellin and supporter of Afonso V. According to Palencia, the Portuguese army was composed of about 1,000 Knights (of which 250 were Castilians), plus infantry.
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This chronicle, written in Latin, covers the time from the end of the reign of John II of Castile to the year 1481, including the reign of Henry IV of Castile; Henry IV’s war with Prince Alfonso; the War of the Castilian Succession; the consolidation of Castile and Aragon under Ferdinand and Isabella; and the signing of the Treaty of Alcáçovas.
In the War of the Castilian Succession, he supported the Catholic Monarchs against his presumed daughter Juana.