In West Philadelphia's Parkside community Columbia Avenue runs between North 51st and Lindenwood Streets; between North Peach and 54th Streets in Wynnefield; North 59th and 63rd Streets in Overbrook; and its final portion between Wynnewood Road and North 64th Street also in Overbrook.
Wynnefield Heights is the home of the Presidential City Apartments, WPVI-TV Channel 6, the City Line shopping center, Crowne Plaza Hotel, Hilton Hotel, TGI Friday's, Target (opened on July 29, 2007 on the former Adam's Mark Hotel site), the Belmont Water Treatment Plant and Reservoir, and the Pennsylvania State Police Barracks (Troop K).