X-Nico

unusual facts about chromosome 11



Aniridia

The AN2 region of the short arm of chromosome 11 (11p13) includes the PAX6 gene (named for its PAired boX status), whose gene product helps regulate a cascade of other genetic processes involved in the development of the eye (as well as other nonocular structures).


see also

Wilms' tumor

Mutations of the WT1 gene on chromosome 11 p 13 are observed in approximately 20% of Wilms' tumors.