X chromosome | Y chromosome | Philadelphia chromosome | polytene chromosome | Human Y-chromosome DNA haplogroup | An inversion loop in the A arm of a chromosome from an ''Axarus |
The defective gene associated with LCCS1 is mRNA export mediator GLE1 at chromosome 9q34.
Tyrosine kinase inhibitors such as imatinib (marketed as Gleevec) have been developed to treat chronic myeloid leukemia (CML), in which the BCR-ABL fusion gene (the product of a reciprocal translocation between chromosome 9 and chromosome 22) is present in >95% of cases and produces hyperactivated abl-driven protein signaling.