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In May 2004, Tweedy checked himself into a rehabilitation clinic in Chicago, Illinois due to chronic migraine headaches, anxiety attacks, and clinical depression.
He is the Founder of the Black Dog Institute, an organization based at the Prince of Wales Hospital in Randwick, New South Wales, that focuses on the treatment of mood disorders, in particular clinical depression and bipolar disorder.
Although clinical trials only revealed an increased risk of insomnia, post-marketing surveillance showed that the drugs are associated with a possible increase in suicidal behavior and other side effects such as agitation, aggression, anxiousness, dream abnormalities and hallucinations, depression, irritability, restlessness, and tremor.
Jack Dreyfus, founder of the Dreyfus Fund, became a major proponent of phenytoin as a means to control nervousness and depression when he received a prescription for Dilantin in 1966.
A famous patient was the poet Ingrid Jonker who was admitted with depression in the 1960s; she later recounted her experiences in several poems.
In 1952, suffering from clinical depression and emotional problems, he admitted himself into the Maudsley Psychiatric Hospital in London.
Albert Gjedde’s collaborations focus on experiments with volunteer subjects and patients that explore the lesions and degeneration of brain tissue in disorders such as epilepsy, ludomania, Parkinson's disease, stroke, depression, and somatizing disorders, as well as disorders related to addiction.
Saxelby's uncle, Kevin, played for Nottinghamshire between 1978 and 1990, while another uncle, Mark, died in 2000 of disputed causes, posited either as weedkiller poisoning or suicide due to clinical depression.