In collaboration with his supervisors, Arturo Rosenblueth and Hallowell Davis, he analyzed the cycle of excitability of cortex neurons (nerve cells) after the convulsive phenomena, and was the first to identify an important phenomenon, that of a decrease of the excitability which spread in increasing circles around the initial focus, which he named spreading depression.
Marino discharged himself the same night and left with fellow wrestler Mal Sanders but suffered from a convulsive attack as they travelled on the M20 motorway.
Electroconvulsive therapy, or electroshock, a psychiatric treatment in which seizures are electrically induced, or its predecessor metrazol/cardiazol convulsive therapy