X-Nico

3 unusual facts about neuron


Biotinylated dextran amine

They can be used for labeling the source as well as the point of termination of neural connections and therefore to study neural pathways.

Large numbers

The number of neuronal connections in the human brain (estimated at 1014)

Motion aftereffect

Neurons coding a particular movement reduce their responses with time of exposure to a constantly moving stimulus; this is neural adaptation.


ANK3

The protein encoded by this gene, ankyrin-3 is an immunologically distinct gene product from ankyrins ANK1 and ANK2, and was originally found at the axonal initial segment and nodes of Ranvier of neurons in the central and peripheral nervous systems.

Aristides Leão

In collaboration with his supervisors, Arturo Rosenblueth and Hallowell Davis, he analyzed the cycle of excitability of cortex neurons (nerve cells) after the convulsive phenomena, and was the first to identify an important phenomenon, that of a decrease of the excitability which spread in increasing circles around the initial focus, which he named spreading depression.

BRAIN Initiative

The BRAIN Initiative (Brain Research through Advancing Innovative Neurotechnologies, also referred to as the Brain Activity Map Project) is a proposed collaborative research initiative announced by the Obama administration on April 2, 2013, with the goal of mapping the activity of every neuron in the human brain.

Compartmental modelling of dendrites

Originally the dendrites were thought to have constant conductance and current but now it has been understood that they may have active Voltage-gated ion channels, which influences the firing properties of the neuron and also the response of neuron to synaptic inputs.

Connectome

Briefly, the approach consists of (1) labelling each neuron with a unique DNA barcode; (2) transferring barcodes between synaptically coupled neurons (for example using PRV); and (3) fusion of barcodes to represent a synaptic pair.

Derrick Spiva

2012 "Neuron Speak" for Los Angeles Electric 8- electric mandolin, electric baritone guitar, tap guitar, electric bass guitar, and four electric guitars.

LIM domain-binding protein family

Nuclear LIM interactor (NLI) / LIM domain-binding protein 1 (LDB1) is located in the nuclei of neuronal cells during development, it is co-expressed with ISL1 in early motor neuron differentiation and has a suggested role in the ISL1 dependent development of motor neurons.

Neuroesthetics

The importance of the visual neuron's varying responses to the orientation and presence of edges has previously been proven by David H. Hubel and Torsten Wiesel.

Pre-locus coeruleus

Subsequently, it was discovered that every c-Fos-positive neuron in the pre-LC (after sodium deprivation) also expresses the transcription factor FOXP2.

Premovement neuronal activity

Spike-triggered averaging is a way to measure the activity of one cortical motor neuron, on a group of lower motor neurons in the spinal cord.

Robert B. Darnell

His laboratory cloned and characterized the neuron-specific splicing factors Nova1 and Nova2, and developed the HITS-CLIP technique that is used to map the sites of regulatory interactions between RNA binding proteins and their target RNA sequences.

Seletracetam

The dual effect of seletracetam is an overall decrease in the amount of action potential due to binding at N-type channels, which prevents over-excitation of the neuron, as well as a decrease in neurotransmitter release as a product of cellular excitation due to the interaction of the drug with SV2A, which reduces the spread of excitation to nearby cells.


see also