He has extensively contributed in the areas of drug targeting in parasitic diseases and membrane phospholipids transbilayer dynamics, and is currently working on elucidation of actin cytoskeletal network in Leishmania.
alpha-dystroglycan is extracellular and binds to merosin alpha-2 laminin in the basement membrane, while beta-dystroglycan is a transmembrane protein and binds to dystrophin, which is a large rod-like cytoskeletal protein, absent in Duchenne muscular dystrophy patients.
This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate (HGS).
mDia, or mammalian diaphanous, a Rho effector protein involved in cytoskeletal polymerisation (see DIAPH1)