Cystic fibrosis transmembrane conductance regulator | Transmembrane protein | OmpA-like transmembrane domain |
The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain.
The encoded protein is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel.
The functions of collagen XXIII are still unknown, although it is believed that they could be similar to other transmembrane proteins, such as collagen XIII.
The viral envelope, obtained by budding through membranes of the ER and/or Golgi apparatus, invariably contains two virus-specified (glyco)protein species, S and M. Glycoprotein S comprises the large surface projections, while the M protein is a triple-spanning transmembrane protein.
The protein encoded by this gene is a hydrophobic protein that contains 2 predicted transmembrane domains and a putative ER localization signal near the C-terminus.
alpha-dystroglycan is extracellular and binds to merosin alpha-2 laminin in the basement membrane, while beta-dystroglycan is a transmembrane protein and binds to dystrophin, which is a large rod-like cytoskeletal protein, absent in Duchenne muscular dystrophy patients.
Once both of these factors were identified Racker was able to confirm Peter D. Mitchell's hypothesis that contrary to popular opinion, ATP synthesis was not coupled to respiration through a high-energy intermediate but instead by a transmembrane proton gradient.
The receptors for EV71 and CVA16 have been identified as P-selectin glycoprotein ligand-1 and scavenger receptor class B, member 2 (SCARB2); both are transmembrane proteins.
A polyclonal caprine antibody is in phase II human clinical trials that targets, among others sites, the GP41 transmembrane glycoprotein.
The IL-1 receptor accessory protein (IL1RAP) is a transmembrane protein that interacts with IL-1R and is required for IL-1 signal transduction.
Other members of the JAM family of transmembrane proteins include JAM1, JAM2 and JAM3.
Mercury transporter (MerF) is a transmembrane bacterial transporter of mercury ions.
A transmembrane nitrate reductase that can function as a proton pump (similar to the case of anaerobic respiration) has been discovered in a diatom Thalassiosira weissflogii.
PtdIns(3,4)P2 is dephophosphorylated by the phosphatase INPP4B on the 4 position of the inositol ring and by the TPTE (transmembrane phosphatases with tensin homology) family of phosphatases on the 3 position of the inositol ring.
This gene encodes a member of the POP family of proteins which contain three putative transmembrane domains.
CD36 and scavenger receptor class BI (SR-BI) are identified as oxidized LDL receptors and classified into class B. Both proteins have two transmembrane domains, and they are concentrated in a specific plasma membrane microdomain, the caveolae.
Vpu interacts with tethrin by interacting with the protein at its transmembrane domain and recruiting β-TrCP2, which causes ubiquitination and degradation of tetherin.
The homologues to Ci-VSP in mammals are called Transmembrane phosphatases with tensin homology, or TPTEs.