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He was an early member of the gay rights movement and attended the first national lesbian and gay gathering, the West Coast Gay Liberation Conference, which took place in 1969 in Berkeley.
Historian Joanne Meyerowitz documented transphobia within the gay rights movement in the mid 20th century in response to publicity surrounding the transition of Christine Jorgensen.
In a review of Kepner’s 1998 book, Rough News, Daring Views: 1950s' Pioneer Gay Press Journalism, historian William Armstrong Percy III wrote, "the Gay rights movement had three remarkable pioneers. Two—Harry Hay and Dorr Legg—have long been recognized, whereas the contribution of the third—Jim Kepner—has never been adequately documented…" Percy goes on to say “Kepner’s articles (in the book) record not only the past of the gay rights movement but also its soul.”