However, new evidence indicates that a multimeric complex (Granzyme B, perforin, and granulysin) can enter a cell through the mannose 6-phosphate receptor (or another receptor found in tumor cells) and is enclosed in a vesicle (a sac).
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Granzyme secretion can be detected and measured using Western Blot or ELISA techniques.
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Granzyme secreting cells can be identified and quantified by flow cytometry or ELISPOT.
granzyme |
Natural Killer T cells can share other features with NK cells as well, such as CD16 and CD56 expression and granzyme production.