histone H3 | Histone H3 | Histone H2B | Histone H2A | Histone H4 | O-6-methylguanine-DNA methyltransferase | Histone deacetylase | 3,7-dimethylquercetin 4'-O-methyltransferase | Methyltransferase | methyltransferase | L-isoaspartyl methyltransferase | DNA methyltransferase | 8-hydroxyquercetin 8-O-methyltransferase | 3-methylquercetin 7-O-methyltransferase |
It interacts with chromatin, the histone methyltransferase G9a (responsible for the mono- and dimethylation of histone 3 lysine 9, H3K9), and the Polycomb Repressive Complex 2, PRC2, (responsible for the trimethylation of H3K27).
STAT5 can also form homo-tetramers, usually in concert with the histone methyltransferase EZH2, and act as a trancriptional repressor.
It can also be associated with mutations in the histone methyltransferase NSD1 gene on chromosome 5q35.