V-ATPase 116 kDa isoform a2 is a subunit of the vacuolar ATPase (v-ATPase), an heteromultimeric enzyme that is present in intracellular vesicles and in the plasma membrane of specialized cells, and which is essential for the acidification of diverse cellular components.
AFP-L3, an isoform of AFP which binds Lens culinaris agglutinin, can be particularly useful in early identification of aggressive tumors associated with HCC.
Heme oxygenase 2 (HO-2) is a constitutive isoform that is expressed under homeostatic conditions.
For DQ6, however, cis-isoform pairing only occurs with DQ1 α-chains.
IMAB362 is a monoclonal antibody against isoform 2 of Claudin-18.
Further, heightened levels of lactate dehydrogenase, specifically the anaerobic isoform- LDH-A in the heart and muscles of S. alascanus, suggests an adaptive mechanism for ATP production during low oxygen availability.
Together with UGT2B4, UGT2B7 is capable of glucosidation of hyodesoxycholic acid in the liver, but, unlike the 2B4 isoform, 2B7 is also able to glucuronidate various steroid hormones (androsterone, epitestosterone) and fatty acids.