A small specimen of ''Mopalia mucosa'' covered in and surrounded by encrusting ''Lithothamnion |
In 1929 Mallory and Soma Weiss, a physician at Harvard, described 15 cases of severe, painless hemorrhage caused by a tear in the mucosa of the esophagus or gastroesophageal junction preceded by vomiting in alcoholic patients.
Esophageal lichen planus, affecting the esophageal mucosa.
They may instead develop proctitis, inflammation limited to the rectum (the distal 10–12 cm) that may be associated with anorectal pain, tenesmus, and rectal discharge, or proctocolitis, inflammation of the colonic mucosa extending to 12 cm above the anus and associated with symptoms of proctitis plus diarrhea or abdominal cramps.