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In August 2011, a report, based on NASA studies with meteorites found on Earth, was published suggesting hypoxanthine and related organic molecules, including the DNA and RNA components adenine and guanine, may have been formed extraterrestrially in outer space.
This finding lends support to the theory that organic molecules that can lead to life (as we know it on Earth) can form in space.
Hückel's rule, a method of determining aromaticity in organic molecules
A graduate student, Stanley Miller, and his professor, Harold Urey, performed an experiment that demonstrated how organic molecules could have spontaneously formed from inorganic precursors, under conditions like those posited by the Oparin-Haldane Hypothesis.
The first demonstration of organic total synthesis was Friedrich Wöhler's synthesis of urea in 1828, which demonstrated that organic molecules can be produced from inorganic precursors, and the first commercialized total synthesis was Gustaf Komppa's synthesis and industrial production of camphor in 1903.