Ancrod is prepared from the crude venom of the Malayan pit viper (Agkistrodon rhodostoma, also termed Calloselasma rhodostoma) and belongs to the group of proteolytic enzymes.
In Italy, a survey was conducted in the vicinity of Rome, and a low level of contamination was found; all strains were proteolytic C. botulinum type A or B.
Historical treatment of food bolus obstruction included administration of proteolytic enzymes (such as meat tenderizers), or even acidic substances, such as Coca-Cola with the purpose of degrading the meat that was blocked; however, it is possible that these methods may increase the risk of perforation of the esophagus.
MOWSE, a method for identification of proteins from the molecular weight of peptides created by proteolytic digestion
#** A. sojae: This fungus also has a high proteolytic capacity.