Born Ana de Lobera y Torres in Medina del Campo in the Province of Valladolid, her parents were Diego de Lobera and Francisca Torres, who also had a son called Cristóbal, who became a Jesuit.
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The village of Wamba in the province of Valladolid, Spain has an impressive ossuary of over a thousand skulls inside the local church, dating from between the 12th and 18th centuries.
In the province of Valladolid with Alonso Berruguete he conducted in 1523 the altarpiece of the chapel of the monastery at Olmedo, Valladolid.