Sambucus nigra | Centaurea nigra | Pinus nigra | Juglans nigra | Fraxinus nigra | Carex nigra | Brassica nigra | Populus nigra | Tinea nigra | Substantia gelatinosa of Rolando | Substantia ferruginea | Prosopis nigra | Porta Nigra | ''Populus nigra'', originating in the United States from plantings by André Michaux | M. nigra | Mined leaf of ''Centaurea nigra | Leaf of ''Ballota nigra | Hoplocorypha nigra | Gila nigra | Betula nigra | A shoot of ''Centaurea nigra |
Carbidopa is used in the treatment of, among other diseases, Parkinson's disease (PD), a condition characterized by death of dopaminergic neurons in the substantia nigra.
DMT1 expression is found to be increased in the substantia nigra of Parkinson's patients and in the ventral mesencephalon of animal models intoxicated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) - a neurotoxin widely used experimentally to produce Parkinsonian symptoms.