She appears as a regular during the third through sixth seasons, despite the fact that there are many episodes in which she does not appear, a fact consistent with real life, where the First Lady must perform official duties all over the country and therefore cannot stay constantly with her husband at the White House.
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Her decision to medicate her husband, in violation of several American Medical Association rules, leads her to voluntarily give up her medical license for the duration of her stay in the White House.
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It is only after he collapses and is confronted by Leo that she reveals their secret to a member of the White House senior staff.
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