He was the lead House sponsor of the Kefauver Harris Amendment, an amendatory act to the federal Pure Food and Drug Act, the law that mandates that pharmaceutical companies disclose the side effects of medications approved by the United States Food and Drug Administration for sale in the United States.
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This decision met with strong opposition and in August 2013 campaigners, including the Campaign to Protect Rural England (CPRE), the Surrey Green Party and the Leatherhead Residents' Association, won a High Court appeal to overturn that decision, on the basis that the project would have an adverse effect on a landscape and area of outstanding natural beauty, and that Surrey did not need another golf course, having 141 already.
They also had the adverse effect of being used by the French Revolutionary Army, after their invasion of Flanders in 1790, to requisition the best paintings for transport to the Musée Central des Arts in the Louvre, Paris.
The widespread addition of WAN optimization devices is having an adverse effect on most network monitoring tools -- especially when it comes to measuring accurate end-to-end response time because they limit round trip visibility.
Large foreign mining companies are in the causing adverse effect to the culture and traditions of the indigenous Subanon and even the poor Settlers.