X-Nico

2 unusual facts about Analgesic


Analgesic

Research suggested that most of the adverse effects of NSAIDs were mediated by blocking the COX1 (constitutive) enzyme, with the analgesic effects being mediated by the COX2 (inducible) enzyme.

Radoslav Velikov

He nevertheless took part in the Olympics thanks to painkillers.


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analgesic | Analgesic |

A535

RUB A535, a topical analgesic manufactured by Church & Dwight

APAP

Paracetamol, an analgesic drug, also known as APAP from active ingredient acetyl-para-aminophenol

Beta-endorphin

It is an agonist of the opioid receptors, with evidence suggesting it serves as the endogenous ligand of the μ-opioid receptor, the same receptor to which the chemicals extracted from opium, such as morphine, have their analgesic and addictive effects (indeed, the μ-opioid receptor was named based on its most renowned ligand, morphine).

C23H22O7

Lactucopicrin, a bitter substance that has a sedative and analgesic effect

C24H26N2O4

Nicodicodeine, an opiate derivative developed as a cough suppressant and analgesic

Charles Romley Alder Wright

Heinrich Dreser, a chemist at Bayer Laboratories continued to test heroin and Bayer marketed it as an analgesic and "sedative for coughs" in 1888.

Dolorimeter

In 1940, James D. Hardy, Harold G. Wolff and Helen Goodell of Cornell University introduced the first dolorimeter as a method for evaluating the effectiveness of analgesic medications.

Interstitial nephritis

Common causes include infection, or reaction to medication (such as an analgesic or antibiotics such as Methicillin (Meticillin).

Pain disorder

According to a study performed at the Leonard M. Miller School of Medicine, antidepressants have an analgesic effect on patients suffering from pain disorder.

Penthrox inhaler

The Penthrox inhaler, manufactured and marketed by Medical Developments International (Melbourne, Victoria, Australia), is a hand-held inhaler device which can be used for the self-administration of methoxyflurane for analgesia (relief of pain).

Puritan Bennett

1997: Nellcor Puritan Bennett became a part of Mallinckrodt, a medical products company with product lines in respiratory care, diagnostic imaging and analgesic pharmaceuticals.

TROX-1

It was developed as a potential analgesic after the discovery that the selective ziconotide is an active analgesic with similar efficacy to strong opioid drugs but comparatively milder side effects.


see also