Another theory, supported only by vague documentary evidence, suggests that in 1456 Antonello visited Milan, where he might have met Van Eyck's most accomplished follower, Petrus Christus.
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The monumental composition is taken directly from the tradition of Holy Conversations in the Venetian School, inaugurated by Antonello da Messina's San Cassiano Altarpiece.
After his death the Roman statues and Italian paintings by Barocci, Bassano, Bellini, Paris Bordone, Pordenone, Palma Vecchio Giorgione, Lorenzo Lotto, Parmigianino, Guido Reni, Giulio Romano, Tintoretto, Titian, Andrea Schiavone, Perugino, Antonello da Messina and Paolo Veronese were shipped to his brother in Amsterdam.
Other highlights include works by the most famous Renaissance and Baroque painters, including Antonello da Messina (Portrait of a Man), Titian, Sebastiano del Piombo, Caravaggio, Rubens, Van Dyck, Murillo, Rembrandt and Frans Hals and portraits by Domenico Ghirlandaio and Vittore Carpaccio.
Antonello da Messina's work had a direct influence on Albrecht Dürer and Martin Schongauer and through the latter's engravings, countless artists including the German, Dutch and English schools of stained glass makers extending into the early 20th century.