In 1978, Alfred Alberts and colleagues at Merck Research Laboratories discovered a new natural product in a fermentation broth af Aspergillus terreus, their product showed good HMGR inhibition and they named the product mevinolin, which later became known as lovastatin.
Since the 1960s, it is produced industrially by fermentation of carbohydrates such as glucose using Aspergillus terreus.
Aspergillus | Aspergillus flavus | Aspergillus niger | Aspergillus fumigatus | Aspergillus versicolor | Aspergillus terreus | Aspergillus parasiticus | Aspergillus ochraceus | Aspergillus sojae | Aspergillus oryzae | Aspergillus nidulans |