The town, which was originally called Johnston Station, had its beginnings in the 1840s when the Atlantic and Gulf Railroad established a stop referred to as "Four and a Half".
Atlantic Ocean | Atlantic | Atlantic Records | Gulf War | Gulf of Mexico | Atlantic City, New Jersey | Baltimore and Ohio Railroad | Pennsylvania Railroad | Persian Gulf | Union Pacific Railroad | Atlantic City | Underground Railroad | Gulf Oil | New York Central Railroad | The Atlantic | Gulf of California | Alaska Railroad | Gulf of Tonkin | Gulf | Erie Railroad | Central Pacific Railroad | Illinois Central Railroad | Gulf of Finland | First Transcontinental Railroad | Atlantic League of Professional Baseball | Atlantic Coast Conference | Gulf of Guinea | Gulf of Carpentaria | Gulf Coast of the United States | Florida Atlantic University |
Jesup was founded in 1856 as a depot at the junction of the Macon and Brunswick Railroad and the Atlantic and Gulf Railroad.