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2 unusual facts about Bone marrow


Andover workhouse scandal

In August 1845 rumours began to circulate around Andover that inmates of the town's workhouse were being deprived of food and had taken to eating the marrow from horse, dog and cattle bones which they were employed to crush to produce bone meal fertiliser.

Puchero

The cuts of meat used are particularly important: if possible, ossobuco; otherwise beef cuts with marrow or poultry (used in puchero de gallina) can be substituted.


Ashoka's Hell

A particular narration detailed how Samudra, while tortured in a cauldron full of boiling water, human blood, bone marrow and excrement, caused the contents of the cauldron to cool down and then sat meditating cross-legged on a lotus sprouting from the fluid.

Carlos Jorge Neto Martins

On 15 November 2011, during Portugal's Euro 2012 playoff home fixture against Bosnia and Herzegovina, it was announced that Martins' three-year-old son Gustavo suffered from a rare bone marrow condition, needing an urgent transplant.

Gemtuzumab ozogamicin

Serious side effects included severe myelosuppression (suppressed activity of bone marrow, which is involved in formation of various blood cells found in 98% of patients), disorder of the respiratory system, tumor lysis syndrome, Type III hypersensitivity, venous occlusion, and death.


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2013 Huang Case in Qatar

She also had recent blood tests showing severely low levels of a certain type of leukocytes that may have been a sign of an underlying bone marrow condition.

Aleca Hughes

She organized a bone marrow donor drive and the Goals for Mandi fundraiser for teammate Mandi Schwartz.

Ayelet Galena

The Galena family partnered with Gift of Life Bone Marrow Foundation and DKMS Americas to set up many drives in the hopes of finding Ayelet a perfect bone marrow donor match.

Bellerose, Queens

Shannon Tavarez - Broadway actress; advocate for bone-marrow donation.

Bodily integrity

In McFall v. Shimp, the court ruled that a person cannot be forced to donate body parts like bone marrow, even if such a donation would save another person's life.

Daniel Kraft

He completed the Harvard combined residency in Internal Medicine and Pediatrics at the Massachusetts General Hospital and the Boston Children's Hospital, before returning to Stanford for clinical fellowship training in hematology/oncology and bone marrow transplantation and a post-doctoral fellowship with Dr. Irving Weissman.

Devaanshi Mehta

She underwent a bone marrow transplant in April 2007 and a top up of bone marrow in February 2008 at Great Ormond Street Hospital in London.

Eran Thomson

He postponed a Bone Marrow Transplant in 1999 in favor of an experimental treatment, now commonly known as Gleevec (Imatinib).

Gift of Life Bone Marrow Foundation

Gift of Life was founded following a successful bone marrow registration drive to save the life of Jay Feinberg, a 23-year-old analyst with the Federal Reserve.

Hematopoietic stem cell transplantation

Georges Mathé, a French oncologist, performed the first European bone marrow transplant in 1959 on five Yugoslavian nuclear workers whose own marrow had been damaged by irradiation caused by a Criticality accident at the Vinča Nuclear Institute, but all of these transplants were rejected.

HSCT

Hematopoietic stem cell transplantation, a medical procedure involving transplantation of bone marrow or other blood-forming cells.

Mart, Texas

E. Donnall Thomas, 1990 Nobel Laureate in Physiology or Medicine who showed that it was possible to transplant bone marrow to save the lives of patients dying from blood cancer and other blood disorders.

Michelle Maykin

Maykin’s efforts received support from many celebrities in the Asian American community, such as American television personality Yul Kwon, who helped raise awareness for Project Michelle and the need for more bone marrow donors in the Asian American and other ethnic communities.

National Organ Transplant Act of 1984

In 2009, a public interest law firm (The Institute for Justice) sued to allow donors to be compensated for giving bone marrow.

Starr Manning

When Starr is diagnosed with aplastic anemia Alex Olanov willingly donates her bone marrow to save her life.

Suresh H. Advani

He gained experience in the field of bone marrow transplantation from the Fred Hutchinson Cancer Research Center, Seattle, Washington.

Tendinitis

Mesenchymal stem cells, derived from a horse's bone marrow or fat, are currently being used for tendon repair in horses.

Total body irradiation

Early research in bone marrow transplantation by E. Donnall Thomas and colleagues demonstrated that this process of splitting TBI into multiple smaller doses resulted in lower toxicity and better outcomes than delivering a single, large dose.

Transplantable organs and tissues

Stem cell transplantation was pioneered using bone-marrow-derived stem cells by a team at the Fred Hutchinson Cancer Research Center from the 1950s through the 1970s led by E. Donnall Thomas, whose work was later recognized with a Nobel Prize in Physiology and Medicine.

University of Nottingham Medical School

The Nottingham branch of Medsin supports a range of student charities - two of these, Marrow (supporting the Anthony Nolan Trust by encouraging students to join the UK bone marrow register) and the Kenyan Orphan Project (supporting several ventures in Kisumu, Kenya) have since spread to other universities in the UK.

Waldenström's macroglobulinemia

Bone marrow tumour cells express the following antigen targets CD20 (98.3%), CD22 (88.3%), CD40 (83.3%), CD52 (77.4%), IgM (83.3%), MUC1 core protein (57.8%), and 1D10 (50%).