Ellagitannins extracted from the pericarps of Punica granatum, the pomegranate, such as punicalin, punicalagin, granatin B, gallagyldilactone, casuarinin, pedunculagin and tellimagrandin I, are highly active carbonic anhydrase inhibitors.
inhibitor | Acetylcholinesterase inhibitor | Selective serotonin reuptake inhibitor | Enzyme inhibitor | enzyme inhibitor | Metalloprotease inhibitor | Matrix metalloproteinase inhibitor | Inhibitor | Farnesyltransferase inhibitor | COX-2 inhibitor | ALK inhibitor | ACE inhibitor |
Renal tubular acidosis failure of HCO3- resorption(i.e., proximal renal tubular acidosis, or overdose of carbonic anhydrase inhibitor) or failure of H+ secretion (i.e. in distal renal tubular acidosis)