It is being tested as a potential drug treatment in children suffering from Hutchinson-Gilford Progeria Syndrome.
In the case of the K- and N-Ras forms of Ras, when cells are treated with FTIs, these forms of Ras can undergo alternate prenylation in the form of geranylgeranylation.
inhibitor | Acetylcholinesterase inhibitor | Selective serotonin reuptake inhibitor | Enzyme inhibitor | enzyme inhibitor | Metalloprotease inhibitor | Matrix metalloproteinase inhibitor | Inhibitor | Farnesyltransferase inhibitor | Farnesyltransferase | COX-2 inhibitor | ALK inhibitor | ACE inhibitor |