In 1765 he worked under the progressive and well informed apothecary, C. M. Kjellström in Malmö, and became acquainted with Anders Jahan Retzius, a lecturer at the University of Lund and later a professor of chemistry at Stockholm.
Gay-Lussac coined the word "cyanogène" from the Greek words κυανός (kyanos, blue) and γεννάω (gennao, I create), because cyanide was first isolated by the Swedish chemist Carl Wilhelm Scheele from the pigment "Prussian blue".
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The solubility of gold in a water and cyanide solution was known by 1783 (Scheele), by Bagration in 1843 and Elsner in 1846 who recognized the necessity of oxygen in the process, (a method of exctraction by chlorination (Plattner) considered during 1848 proved uneconomical) this prior to the discovery of an economical method of treatment with potassium cyanide by J.S. MacArthur (with R. and, or, W. Forrest).
In a series of papers he attributed the premature deaths or illnesses of the chemists Joseph Priestley, Carl Wilhelm Scheele, Humphry Davy, William Cruickshank (chemist) and James Woodhouse to chemical poisoning.