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In 1888 the Bretten–Eppingen–Heilbronn section of the line was duplicated as part of a military supply route from central Germany via Nuremberg, Crailsheim, Heilbronn, Bretten, Bruchsal, Zweibrücken in the Saarland to Lorraine.
The Nuremberg–Crailsheim railway is a major railway in the north of the German states of Bavaria and Baden-Württemberg, which links Nuremberg, Ansbach and Crailsheim.