He appears in Megadeth's music video for the song "Of Mice and Men", the Arsenal of Megadeth DVD, and (in cartoon form) the band's cameo in an episode of Duck Dodgers.
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The game involves Duck Dodgers in the 24th and a ½ Century, as told in the classic Looney Tunes stories created by Chuck Jones.
In the science fiction television series Babylon 5, the character of Michael Garibaldi is a fan of Daffy Duck, and describes "Duck Dodgers" as his "second favorite thing in the universe".