X-Nico

unusual facts about Testosterone


Echinops echinatus

Testosterone (3 mg kg−1, s.c.) was administered to the rats along with the test extracts (50 and 100 mg kg−1, p.o.) for a period of 28 days.


4-Androstenediol

Patrick Arnold holds a 1999 patent on "Use of 4-androstenediol to increase testosterone levels in humans".

Androstenediol

4-Androstenediol, a steroid androgen which acts as a prodrug to testosterone

5-Androstenediol, a steroid androgen which is an endogenous precursor for testosterone

Ángel Guillermo Heredia Hernández

He created a number of doping substances and methods, with a combination of testosterone, growth hormone and EPO being his most successful.

Carlo Santuccione

Doping products such as Testosterone anabolic steroids, EPO, Aranesp (Darbepoetin alfa) and blood transfusion equipment (Blood doping) were found and investigations were opened against 138 athletes (15 of whom were professional cyclists).

Congenital adrenal hyperplasia due to 11β-hydroxylase deficiency

Because 11β-hydroxylase activity is not necessary in the production of sex steroids (androgens and estrogens), the hyperplastic adrenal cortex produces excessive amounts of DHEA, androstenedione, and especially testosterone.

Daniela Yordanova

She tested positive for testosterone in an out-of-competition doping test in Sofia on 13 June 2008, which eventually got her kicked out of the 2008 Summer Olympics.

DHT

Dihydrotestosterone, a potent endogenous androgenic hormone, derived from testosterone

Emmanuel Garcia

On June 2nd 2010 The New York Mets sent an official letter from Major League Baseball informing Garcia he tested positive for high levels of human chorionic gonadotropin, which is illicitly used after an anabolic steroid cycle to jump-start the body's production of testosterone .

Ergogenic use of anabolic steroids

According to sports physician John Ziegler, the first confirmed use of an anabolic steroid in an international athletic competition was at the weightlifting championships in Vienna in 1954, when the Russians weightlifters used testosterone.

Ethisterone

The first orally active progestin, ethisterone (pregneninolone, 17α-ethynyltestosterone or 19–norandrostane), the 17α-ethynyl analog of testosterone, was synthesized in 1938 by Hans Herloff Inhoffen, Willy Logemann, Walter Hohlweg, and Arthur Serini at Schering AG in Berlin and marketed in Germany in 1939 as Proluton C and by Schering in the U.S. in 1945 as Pranone.

Flutamide

LH stimulates the testes to produce testosterone, which is metabolized to DHT by the enzyme 5α-reductase.

Hirsutism

Their levels of Sex hormone-binding globulin (SHBG) increased, which reduced the amount of free testosterone in their blood.

Larry Bigbie

According to the report, Bigbie admitted to purchasing and using a variety of performance-enhancing substances from Kirk Radomski from 2001 to 2005, including human growth hormone, Deca-Durabolin, Sustanon, testosterone, and anti-estrogen drugs.

Progestin-induced virilisation

In general, pregnane derivatives (progesterone, dydrogesterone, 17α-hydroxyprogesterone caproate, medroxyprogesterone acetate, megestrol acetate, etc.) do not virilize even in high dose; testosterone derivatives (ethisterone) and 19-nortestosterone (norethisterone, norethisterone acetate, etc.) generally virilize, but there are exceptions (e.g. norethynodrel) that do not.

Ring finger

The ratio between index and ring finger is believed to be linked to exposure to testosterone in the womb.

The cream

After an investigation, it was revealed that many top baseball athletes were connected with THG; the list included stars such as Jason Giambi, who would also confess to using human growth hormone and testosterone, Gary Sheffield, who admitted using the cream and the clear, albeit unknowingly.

Trevor Graham

An unsent letter written by BALCO's Victor Conte to the U.S. Anti-Doping Agency described the use of an oral testosterone by Graham that "will clear the body and be undetectable in urine in less than a week after discontinuing use." At the end of the letter, Gatlin was one of four athletes identified as using the drug.


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