He participated in the first papal conclave of 1590 that elected Pope Urban VII; the second papal conclave of 1590 that elected Pope Gregory XIV; the papal conclave of 1591 that elected Pope Innocent IX; and the papal conclave of 1592 that elected Pope Clement VIII.
He was the son of Ambrogio Spinola, 1st Marquis of the Balbases, (Genoa, Italy, 1569 - 25 September 1630), 1st duke of Sesto, (title awarded in Naples on 2 April 1612), granted the Grandee of Spain on 17 December 1621 with his marquisate, Conqueror of Breda, 1623, Governor of the Duchy of Milan, also a Knight of the Order of the Golden Fleece, 1631, and Giovanetta Bacciadone y Doria (1597–1615).
Filippo Tommaso Marinetti | Filippo Maria Visconti | Filippo Lippi | Eduardo De Filippo | Paul Di Filippo | Filippo Volandri | Ambrogio Spinola, 1st Marquis of the Balbases | Filippo Pozzato | Filippo Palizzi | Filippo Marchese | Filippo de Filippi | Filippo Brunelleschi | Peppino De Filippo | Giambattista Spinola | Filippo Titi | Filippo Terzi | Filippo Strozzi the Younger | Filippo Pacini | Filippo Maniero | Filippo Decio | Filippo Baldinucci | António de Spínola | San Giacomo Filippo | Giovanni Battista Spínola | Giambattista Spínola, Jr | Filippo Valguarnera | Filippo Taglioni | Filippo Strozzi the Elder | Filippo Strozzi | Filippo Salvatore Gilii |